Drug overdose: Definition, risks, signs, and more

However, there is definitely a risk of long term effects which increases with every overdose. It works by removing the opioids from the receptors in the brain, and overturning their depressive effects. Medical personnel may pump the person’s stomach to eradicate the substance and administer activated charcoal or medicines to counteract it. They will also monitor the patient’s vital signs and work to improve them, if necessary.

drug overdose: definition, treatment, prevention, and more

CDC: Injury Prevention and Control: Prescription Drug Overdose

Substance use disorder (SUD) is defined as a problematic pattern of substance use leading to clinically significant impairment or distress. Education and awareness around the harm of using substances, along with the support of friends, parents, and caregivers, can help prevent SUDs. The Stop Overdose website educates drug users on fentanyl, naloxone, polysubstance use, and dealing with stigma. An intentional overdose happens when a person takes too much of a drug (or more of them) too quickly and on purpose.

  • A drug overdose is a medical emergency and can have potentially fatal consequences.1 And in cases of non-fatal overdose, the person may still experience harmful short-term and long-term effects.
  • After calling 911, stay with the individual experiencing an alcohol overdose.
  • Symptoms of drug overdose are greatly determined by the substances abused.
  • Participating jurisdictions share aggregate data on total ED visits and inpatient hospitalizations and line-level data on nonfatal overdoses with CDC annually, with a 6-month lag.
  • Although many drug overdoses involve the use of illegal drugs, it is also possible to overdose on prescription medication.

Drug Overdose: Signs, Symptoms, Effects, and Treatment

The rate of deaths from drug overdose has increased steadily over the past couple of decades. Overdose prevention is a CDC priority that impacts families and communities. Drug overdose is a leading cause of preventable death in the U.S. The primary inhibitory neurotransmitter in CNS is gamma-aminobutyric acid (GABA), which binds to receptors enabling chloride to enter the cell. As alcohol binds to GABA strongly, it activates an inhibitory cascade, which leads to problems such as impaired coordination, sedation, and cognitive dysfunction. In other words, drinking too much too quickly overstimulates GABA pathways and induces symptoms of alcohol poisoning or overdose.

Alcohol overdose

Naloxone (spray or auto-injectable) can reverse an opioid overdose, including heroin, fentanyl, and prescription opioid medications. Administer the naloxone and then stay with the person until emergency services arrive on the scene, or for at least four hours to monitor if their breathing has gone back to normal. Activated charcoal may be used to absorb the drug in the digestive tract, while gastric lavage (stomach pumping) and the administration of intravenous fluids may be used to rapidly eliminate or dilute the drug. Substances to combat the actions of the drug may be administered, such as naloxone in the case of opioid overdose or n-acetylcysteine for acetaminophen overdose. Mechanical ventilation or oxygen therapy may be used for individuals who experience difficulty breathing.

Drug overdose is caused by a rapid and excessively high intake of one or more drugs whose effects overwhelm the brain and body. The mechanism of action that leads to the development of overdose varies from one type of drug to another. Risks of drug abuse include mixing drugs, low tolerance, dropping out of treatment, not knowing enough about the drug, having mental health problems, and method of use. This rise in opioid overdose deaths can be outlined in three distinct waves.

Health Care Providers

These and other life-saving measures can help reduce the long-term health effects of drug overdose. If you misuse drugs, quitting is the best way for you to prevent a drug overdose. Know that certain ways of taking drugs can be riskier than others. Inhaling or injecting drugs may cause them to get to your brain more quickly and also increases your chance of using an amount that can severely harm you. The healthcare provider may be able to use an antidote for certain drug overdoses. For example, the drug naloxone can help reverse the effects of a heroin overdose.

  • Also, since the person overdosing is heavily under the influence, they may not know what is going on or be able to call for help.
  • Before sharing sensitive information, make sure you’re on a federal government site.
  • Treatment enables people to counteract addiction’s disruptive effects on their brain and behavior and regain control of their lives.

People experiencing SUDs have trouble controlling their drug use even though they know drugs are harmful. BetterHelp can connect you to an addiction and mental health counselor. People with severe overdoses may require hospitalization and intensive care.

Understanding the Opioid Overdose Epidemic

The DFC program has been a central component of our nation’s youth substance use prevention strategy, and it provides funding and support to community coalitions to prevent and reduce youth substance use. Inpatient drug overdose: definition, treatment, prevention, and more rehabilitation at a full-time facility provides a supportive environment to help people recover without distractions or temptations. Cognitive-behavioral therapy seeks to help patients recognize, avoid, and cope with the situations in which they’re most likely to use drugs.

It’s not always easy to discern the symptoms of a drug overdose and many people may not realize that are experiencing an overdose when it happens. Also, since the person overdosing is heavily under the influence, they may not know what is going on or be able to call for help. A drug overdose is the ingestion or administration of a drug or drugs in an amount that exceeds recommended levels, resulting in toxicity.

Poisoning by other synthetic narcotics, undetermined, initial encounter. Poisoning by primarily systemic and hematological agents, not elsewhere classified, such as antiallergic and antiemetic drugs, antineoplastic and immunosuppressive drugs, vitamins, etc. Poisoning by drugs primarily affecting the autonomic nervous system, such as anticholinesterase agents, other parasympathomimetics cholinergics, ganglionic blocking drugs, etc. Poisoning by antiepileptic, sedative-hypnotic and antiparkinsonism drugs, such as hydantoin derivatives, iminostilbenes, succinimides and oxazolidinediones, etc. Poisoning by other systemic anti-infectives and antiparasitics, such as sulfonamides, antimycobacterial drugs, antimalarials and drugs acting on other blood protozoa, etc. Generally, the body can process around one unit of pure alcohol per hour.

Opioids are one of the substances that are most dangerous for overdoses, due to the way they function. Opioids are extracted from poppy seeds (or made with synthetic compounds with similar properties) and they interact with opioid receptors in the brain. Keep reading to learn more about drug overdoses, how they happen and a few other very important things you should know.

Department of Health & Human Services’ Overdose Prevention Strategy to address the public health emergency as it continues to evolve. The overdose crisis is an evolving public health crisis; as such, FDA continues to evaluate our approach and make adjustments according to the latest available science and data. If someone is unresponsive and you know they have taken drugs, don’t assume they are simply asleep. Always call an ambulance if you suspect they might have overdosed – you may save their life. If someone is sick or has a weakened immune system, they are at a higher risk for overdose because their body is weakened. Also, the effects of a long term disease such as HIV or hepatitis can wear down the body and put someone more at risk for an overdose.

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